Hi jsue, I have recently been diagnosed with BC which is ER+ so consultant prescribed Anasrozole. I had been on HRT which I stopped as soon as diagnosed and went estrogen cold turkey. I had to have blood tests before starting anastrozole so it was a week later that I started taking it.

I did a bit of reading up and a lot of women suggested taking at night. I’m now 5 days in and was expecting lots of side effects during this time, so far nothing. In fact there has been a massive plus, before I was diagnosed (routine screening) I was diagnosed with massive uterine fibroids that have been causing quite severe sciatica. I have had no real relief from the pain for the last 18mnths until a couple of days ago. It could be coincidence but anastrozole is used to shrink fibroids so maybe I can avoid hysterectomy for a couple of years, when I have got through BC treatment.

Hi [@jSue56]‍ i started on Anastrozole nearly five months ago. I was 8/8 for ER and PR so really needed to be on it. I was really nervous after reading about the side effects but I am feeling good. I have had maybe half a dozen hot flushes in that time. After two weeks I had a small bit of knee and ankle stiffness but that disappeared soon after. No other side effects at all. I was in a dilemma about whether to take in morning or evening but settled on 10pm and have an alarm on my phone as a reminder. As my oncologist said you don't know if you try and I think a lot of women like me get on fine with it. If you don't you are understandably more likely to post how awful it is. Good luck! Xx

Thank you for your reply It’s good to get some reassurance xx