Anyone receiving Denosumab XGEVA

Is anyone here receiving Denosumab XGEVA for metastatic bone cancer

Ive been advised to have this by injection  to slow the progression of the cancer and prevent bone fractures.

Id like to know how well it is tolerated and what side effects you have experienced.

Thanks in advance

Ed

Parents
  • Hi Ed

    I had 3yrs of Denosumab injection but had to stop after issue with tooth extraction.please make sure you have a full dental examination and discussion with your dentist. Advise them you are going on this treatment.

    With any dental treatment other than clean or checkup you will need to stop the Denosumab for a couple of weeks and keep your. Oncologist up to date.

    Really important as I now have mronge of jaw.

    Not nice.

    I wish you well with your treatment. 

    Anything that helps and hives you help can only be a good thing.

    Best Wishes

    Lorraine

  • Hi Lorraine

    Thank you for your reply, Ive been on Denosumab 6 weekly for around 8 months now with no noticible side effects. I had a dental check up and xray at the hospital before starting the treatment which showed no problems. I am extremely susceptible to necrosis of the jaw as I had radiotherapy to my jaw and neck 10 years ago and now an increased chance from the Denosumab. Ive been using prescription high fluoride toothpaste Colgate Duraphat for the last 10 years to reduce dental caries and the possiblity of requiring a tooth extraction. A family member jokes I'm lucky having cancer as I get free toothpaste. As you point out the dentist can do checkups and a clean at the hygeinist. Ive been told that extractions and other work needs to be done at the hospital. I did not know that Denosumab had to be discontinued at this point but I guess that makes sense. I hope that you are getting on Ok .

    Ed

Reply
  • Hi Lorraine

    Thank you for your reply, Ive been on Denosumab 6 weekly for around 8 months now with no noticible side effects. I had a dental check up and xray at the hospital before starting the treatment which showed no problems. I am extremely susceptible to necrosis of the jaw as I had radiotherapy to my jaw and neck 10 years ago and now an increased chance from the Denosumab. Ive been using prescription high fluoride toothpaste Colgate Duraphat for the last 10 years to reduce dental caries and the possiblity of requiring a tooth extraction. A family member jokes I'm lucky having cancer as I get free toothpaste. As you point out the dentist can do checkups and a clean at the hygeinist. Ive been told that extractions and other work needs to be done at the hospital. I did not know that Denosumab had to be discontinued at this point but I guess that makes sense. I hope that you are getting on Ok .

    Ed

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