Hello ANJIE64,

Welcome to Cancer Chat.

I'm sorry to hear about the pains you've been having. Joint pain is a possible side effect of this treatment so, If you haven't already, it might be good idea to discuss this with your healthcare team. They may be able to adjust the dosage if needed. You can read more about letrozole and some of it's side effects on our website and we also have a cancer nurse helpline. If you'd like to discuss this with a nurse over the phone, you can call 0808 800 4040 for free. Lines are open 9 to 5 Monday to Friday.

All the best and I hope things improve.

Moderator Anastasia

Hi Anjie64,

A very warm welcome to the forum.

I am sorry to hear of all that you have been through and know just how difficult it can be to take Letrozole. I had to have both of my knees replaced, as a result of these side-effects. I have had 2 bouts of breast cancer. I had a Lumpectomy the first time, followed by Tamoxifen. Less than a year later, I discovered another cancer in the same breast. This time I had a double mastectomy and changed to Letrozole. The side-effects of the Letrozole were certainly more marked in all of my joints. I understand that this is a common problem. Unfortunately, some 14 years on, I still have problems with all of my joints, but it is hard to tell whether or not this would have happened with the progression of time anyway. I persevered with Letrozole for 6½ years and, despite all of the side-effects, I would do it all again, as I am fortunate enough to now be 15 years from diagnosis. My consultant advised that I tried Starflower Oil Capsules to ease the pain. Unfortunately, I didn't find these of any help.

Have you spoken to your care team about how you feel? They may be able to adjust your dose, or even to prescribe another hormone therapy instead?

Please keep in touch and let us know how you get on. We are always here for you.

Kind regards,

Jolamine xx