Hello ANJIE64,

Welcome to Cancer Chat.

I'm sorry to hear about the pains you've been having. Joint pain is a possible side effect of this treatment so, If you haven't already, it might be good idea to discuss this with your healthcare team. They may be able to adjust the dosage if needed. You can read more about letrozole and some of it's side effects on our website and we also have a cancer nurse helpline. If you'd like to discuss this with a nurse over the phone, you can call 0808 800 4040 for free. Lines are open 9 to 5 Monday to Friday.

All the best and I hope things improve.

Moderator Anastasia

Thankyou anastasia

Hi Anjie64,

A very warm welcome to the forum.

I am sorry to hear of all that you have been through and know just how difficult it can be to take Letrozole. I had to have both of my knees replaced, as a result of these side-effects. I have had 2 bouts of breast cancer. I had a Lumpectomy the first time, followed by Tamoxifen. Less than a year later, I discovered another cancer in the same breast. This time I had a double mastectomy and changed to Letrozole. The side-effects of the Letrozole were certainly more marked in all of my joints. I understand that this is a common problem. Unfortunately, some 14 years on, I still have problems with all of my joints, but it is hard to tell whether or not this would have happened with the progression of time anyway. I persevered with Letrozole for 6½ years and, despite all of the side-effects, I would do it all again, as I am fortunate enough to now be 15 years from diagnosis. My consultant advised that I tried Starflower Oil Capsules to ease the pain. Unfortunately, I didn't find these of any help.

Have you spoken to your care team about how you feel? They may be able to adjust your dose, or even to prescribe another hormone therapy instead?

Please keep in touch and let us know how you get on. We are always here for you.

Kind regards,

Jolamine xx

Hi jolamine

thankyou for responding 

I have an appointment with my oncologist tomorrow so hopefully I will be helped to come to some decision as what to do. I’m in so muc

h pain in my knees and I’m having hot flushing, foul mood and generally crabby. I’m back 13 years to menopause. I can’t go through that again. 
pill let you know how I progress

Hi Anjie,

I hope that all goes well with the oncologist tomorrow and that you find a solution for these side-effects.

Kind regards,

Jolamine xx

I was diagnosed with Parkinson’s disease four years ago. For over two years, I relied on Levodopa and several other medications, but unfortunately, the symptoms kept getting worse. The tremors became more noticeable, and my balance and mobility started to decline quickly. Last year, out of desperation and hope, I decided to try a herbal treatment program from NaturePath Herbal Clinic.

Honestly, I was skeptical at first, but within a few months of starting the treatment, I began to notice real changes. My movements became smoother, the tremors subsided, and I felt steadier on my feet. Incredibly, I also regained much of my energy and confidence. It’s been a life-changing experience I feel more like myself again, better than I’ve felt in years.If you or a loved one is struggling with Parkinson’s disease, I truly recommend looking into their natural approach. You can visit their website at www. naturepathherbalclinic .com

I was diagnosed with Parkinson’s disease four years ago. For over two years, I relied on Levodopa and several other medications, but unfortunately, the symptoms kept getting worse. The tremors became more noticeable, and my balance and mobility started to decline quickly. Last year, out of desperation and hope, I decided to try a herbal treatment program from NaturePath Herbal Clinic.
Honestly, I was skeptical at first, but within a few months of starting the treatment, I began to notice real changes. My movements became smoother, the tremors subsided, and I felt steadier on my feet. Incredibly, I also regained much of my energy and confidence. It’s been a life-changing experience I feel more like myself again, better than I’ve felt in years.If you or a loved one is struggling with Parkinson’s disease, I truly recommend looking into their natural approach. You can visit their website at www. naturepathherbalclinic .com