Prostate cancer - my Dad

Hi Everyone,

First-time posting here—like many, I’ve tended to shy away from cancer until it was staring me in the face.

My dad has been diagnosed with Stage 4 metastatic prostate cancer, which has spread to a single site on his pelvic bone (1cm tumour). I understand this isn’t curable, but with the right treatment, many men live for years. His PSA is quite high (80+), suggesting potential for fast progression, but the limited spread (oligometastatic) gives us some hope.

He’s fit, active, and otherwise healthy—loves golf, walking, and staying on the move. He doesn’t smoke or drink, so I’d like to think his body can handle treatment well.

He started on hormone therapy (ADT) and has tolerated it fine so far, but following his PET scan, it’s clear this won’t be enough long-term. Now, he’s faced with treatment decisions, and I’d love to hear from anyone who’s navigated similar choices.

The three main options presented were:

1. Hormone therapy only

2. Chemotherapy + hormone therapy + androgen inhibitors(aggressive approach but with more side effects)

3. **(Waiting for confirmation of this one but think more tablet led and possible radiotherapy) 

many thanks  

  • Hi GJones1982, and a warm welcome to the forum, though I'm sorry you have to be here and for your dad's diagnosis.

    I have metastatic prostate cancer, for nearly 3 years now, and unlike oligometastatic, which is classed as an early form  of stage 4  prostate cancer, mine had spread to 13 places and due to co-morbidities I was limited to hormone therapy HT and radiotherapy RT, I started HT on diagnosis, with aggressive  RT, 20 fractions 76gy in April 2022 to the whole pelvic area. At my last MDT meeting I had no evidence of cancer, except for 1 lymph node, which will be "treated", with SABR, and I have just 6 weeks ago started treatment plan B. I know just because my cancer can't be detected, doesn't mean it's not there 

    That your dad is fit and healthy is great news, and with only 1 met, will be a big plus with treatment, I understand my treatment doesn't match any of your dad's options, but even in just 3 years prostate cancer treatment has made big strides, and the most important thing on this journey is the trust you have in your team 

    If I had been diagnosed today, I would have opted for triple therapy, (2)I have a few friends who have had it with very good results, but your choice must be the right one for your dad. My best wishes to you both 

    Eddie xx 

  • Hey Eddie 

    Thank you so much for taking the time to reply and share your experience—it really means a lot. I’m sorry you’ve had to go through this, but it’s incredibly inspiring to hear how well you’ve responded to treatment and how far prostate cancer care has come, even in just a few years.

    It’s reassuring to hear that being fit and only having one met could be a positive factor for my dad. I know every case is different, but your perspective helps put things into context and gives me hope that we still have good options ahead.

    Your words about trusting the medical team really resonated with me—it’s such an uncertain road, but knowing we have people with experience and knowledge guiding us is invaluable. I’ll definitely share your thoughts on triple therapy with my dad as he works through his decision.

    Wishing you all the best with your ongoing treatment—I truly hope things continue to work well for you. Thanks again and all the best

    Gaz

    I think we need to get more insight into the potential effects of chemo to perhaps get to a point he feels comfortable going all in with the treatments 

  • Hi Gaz, you are welcome, and thank you for your good wishes. As you have probably read all treatments come with the risk of side effects, which, if any and how hard they affect you is impossible to know beforehand, though fatigue is common to almost everyone to some degree, but by working on your fitness now, this will mitigate it's impact and be helpful through recovery, The main chemo drug for prostate cancer, docetaxel, which for chemotherapy is often quite easy to manage.

    Eddie xx

  • I'm 63yo diagnosed with advanced metastatic prostrate cancer in July aggressive and widespread throughout my bones lower back, spine, neck and lymph modes my PSA was a whopping 1,973 on monthly Hormone therapy injections since diagnosis and enzalutamide tablets for last three months seems to have slowed things down and my PSA results from blood test in December was down to 2.2 so hopeful these two treatments are working for me.

  • Hi Freddy61,  I'm sorry to hear you too have advanced MPCa, it's a tough hand we've been dealt, I too am on HT injections "Prostap3", and Enzalutamide, though only been on Enzalutamide for 6 weeks, so don't know how effective it is for me, but it's good to see it's working for you my friend, that's some drop, and I will have everything crossed it continues helping for some time yet, my best wishes to you.

    Eddie 

  • That’s an incredible drop in PSA—thank you for sharing your journey, and I really appreciate you taking the time to offer insight. It’s so encouraging to hear that the hormone therapy and Enzalutamide are working well for you, especially given how aggressive your diagnosis was.

    While my dad’s situation is different, hearing real experiences like yours helps me feel more hopeful about treatment options and what might be possible for him. I will  share with him so thank you.

    It sounds like you’ve been through a lot, and I admire the strength and resilience it must take to keep pushing forward.

    Wishing you continued success with your treatment, and thanks again for sharing

    Gaz