Hi again.  Just curious why the suggestion was not to have Chemotherapy ?  And how did it come about that your husband had a PSA test?  Hope the biopsy has gone well. With a PSA of 768 I’d be interested to know the Gleason score. It took me a couple of weeks before the expected ‘blood in my urine’ stopped - but there was very little colouring.  

As an aside, on one American cancer site there was a person interviewed who had a PSA of 1150 some 25 years ago - he was now 75. So there is hope for an above average outcome. 

Hi the reason he had a blood test is because he was going to toilet 3 times thro night which he has never done in 34 years so he went to doctors they did bloods then a examination of his prostate which was hard and bigger so so far when we was told he had advanced prostate cancer he had injections the same day which is degaralix he has to have them every month the last week had CT scan and bone scan then today biopsy that's all we know for now no chemo was offered as yet 

Getting up to the toilet was my issue.  However, while it was only once a night it was very unusual for me and regular. This started in May/June 2022.  When I saw the doctor in September 2022 and asked for a PSA test because of it, the female doctor said she thought it was unnecessary and to monitor it.   As nothing changed over the year I wondered if it may be a kidney issue.  So last September I booked a Health Check with the surgery nurse and specifically asked for a PSA test. That’s how I found out - I could and should have found out a year earlier.

Sorry if I repeat what I have written before. However, it seems that the procedure is to get a patient on immediate ADT. My start was with Bicalutamide for 14 days which works to reduce testosterone.  Then a rear end jab of 3.5mg of Decapeptyl good for 30 days for the same. It seems that this jab increases testosterone to being with - hence the Bicalutamide to start. My next jab was on December 1st and is good for 90 days.

From what I have read about chemotherapy which is part of a Triplet procedure with Darolutamide, a procedure that started in 2022, this has to start at three months after a patient initially starts on ADT - check out Chemotherapy on the Prostate Cancer UK website and Google ‘Triplet cancer prostate’

There are several different ADT drug names that do the same thing, so it looks like alternatives are used across the NHS. 

Getting up to the toilet was my issue.  However, while it was only once a night it was very unusual for me and regular. This started in May/June 2022.  When I saw the doctor in September 2022 and asked for a PSA test because of it, the female doctor said she thought it was unnecessary and to monitor it.   As nothing changed over the year I wondered if it may be a kidney issue.  So last September I booked a Health Check with the surgery nurse and specifically asked for a PSA test. That’s how I found out - I could and should have found out a year earlier.

Sorry if I repeat what I have written before. However, it seems that the procedure is to get a patient on immediate ADT. My start was with Bicalutamide for 14 days which works to reduce testosterone.  Then a rear end jab of 3.5mg of Decapeptyl good for 30 days for the same. It seems that this jab increases testosterone to being with - hence the Bicalutamide to start. My next jab was on December 1st and is good for 90 days.

From what I have read about chemotherapy which is part of a Triplet procedure with Darolutamide, a procedure that started in 2022, this has to start at three months after a patient initially starts on ADT - check out Chemotherapy on the Prostate Cancer UK website and Google ‘Triplet cancer prostate’

There are several different ADT drug names that do the same thing, so it looks like alternatives are used across the NHS.