I'm 50 and Iv had breast cancer twice and now a double mastectomy over the last 6 years. Iv felt like I have coped well with it but now I'm also on letrazole I feel very down. However this was triggered by a cancelled major reconstruction op at the last minute due to covid. Everything was focussed towards this op, it's how I got through it. I'm not sure if letrazole is the culprit. It's better than tamoxifen, that made me bleed internally. I had all the tests for ovarian cancer but as soon I they switched me to letrazole I was ok