Letrozole - Eye problems?

Hi everyone I’ve been taking Letrozole for the last few months and had my annual eye examination a few weeks ago. I provided a list of medications I’m taking and as an afterthought added Letrozole. She said that she’d recommend testing every few months because it can cause eye problems (can’t remember condition that she said). 

I mentioned it to my Oncologist and he seemed to ‘poo poo’ it! Saying hundreds of ladies have taken it. Has anyone on here had any eye problems that may be caused by it? 

I’m asking today because I’ve discovered a large blood blast behind my iris - not sore or affecting my sight, but just reminded me to ask. 

Many thanks J

xx

Parents
  • I'm sorry about the conflicting information you've received about this J.

    I've had a quick look on our website and can see that 'eye problems such as blurred vision, cataracts or irritation'  is listed under rare side effects so this may be what the optician is referring to but it may be worth giving our cancer nurses a call about this on 0808 800 4040 (phone lines open Monday - Friday between 9a.m - 5p.m) to find out more.

    Hopefully some of our members who are taking Letrozole will pop by soon to let you know if they've had this problem as well.

    All the best, 

    Steph, Cancer Chat Moderator

Reply
  • I'm sorry about the conflicting information you've received about this J.

    I've had a quick look on our website and can see that 'eye problems such as blurred vision, cataracts or irritation'  is listed under rare side effects so this may be what the optician is referring to but it may be worth giving our cancer nurses a call about this on 0808 800 4040 (phone lines open Monday - Friday between 9a.m - 5p.m) to find out more.

    Hopefully some of our members who are taking Letrozole will pop by soon to let you know if they've had this problem as well.

    All the best, 

    Steph, Cancer Chat Moderator

Children
  • Hi I've been on Letrozole since February 2020 and had an eye test a couple of months ago she said I have the start of cataracts and would now see me yearly to monitor it I told her I was on Letrozole when she asked if my medical history was the same. But I googled Letrozole and eye problems after I got home and it says cataracts can be a rare side effect 

  • Hi I've been.on Letrozole since September 2025 and really suffering with dry eye only in my right eye.

    The tear duct is sore I'm fed up of my eye weeping and I think due to the salt from my tears I'm now getting a split on the outside if my eye too which is sore. I've heard there are 7 x different brands of Letrozole and try to find the one that suits you best ...butvwhen the pharmacy gives you a different one every month think it's playing havoc with my eye.. skin and splitting skin on my fingers that are soooooo itchy at night .....

    Sorry for the moan..  but hey-ho I'm still alive & ALIVE being the word.. I've had mixed invasive ductal and lobular left breadt maste tomorrow axillary LN clearance ER positive HER2 neg also now on ibandronic acid & abemaciclib... I'm a walking pharmacy...

    One day at a time........