Enzalutamide (Xtandi) experiences

Hi 

My father has been fighting prostate cancer for 6 years and 7 months now. 

Six weeks ago the results of a MRI confirmed that the hormone therapy drug that had controlled the cancer had stopped working for him. We were told that the cancer had spread to his lymph nodes in his stomach and that with the high rising PSA result the cancer was on the move to other areas. 

The Drug that he is undecided about is called Enzalutamide, brand name  (Xtandi) and has MDV3100. It is a hormone therapy treatment for men with advanced prostate cancer. 

Side effects are what is stopping my father from starting this medication as the rare side effects are dreadful and the occasional ones not much better. 

We realise that any drug carries side effects and understand that this is his only option to prolong his life. 

What we would like to hera is from anyone who is on this medication, or who knows someone who is please. 

His Onchologist is a great man and has explained that the quality of his remaining time here is what is important which we pappreciate. However, my father is an amazing man and pushes himself beyond expectation to survive this dreadful disease, what he cannot bare the thought of is loosing his memory, seizures and all the other dreadful side effects that this medication may bring to him.  I have promised to find out from like minded people that are going through the same situation, collect their opinion and advice before he makes him mind up whether or not to take the medication. 

Thank you in advance for anyone who can be of some assistance here. 

x

  • Just to keep you updated , oncologist said to stop Enzalutamide, for couple of months to see if my energy and BP increase,as im struggling to get energy to do things .

    My PSA will go up but no choice, and probably have to have increased tablets again .

    i have got other medical issues,so everything will need to be checked if stopping Enzalutamide doesn't help.

    Hope things improve for your dad , remember he can stop if he wants . 

    My oncologist told me there is a new tablet out but no good for me , also, PSMA 617 is just starting trials in UK ask your dad's oncologist about them,it might not be anything but cannot help to ask.

    Take care of yourself remember .

    Billy

  • Thank you again 

    you too 

    regards 

     Mil

  • Enzalutamide immediately halted the doubling of my PSA level and has, in 3+ months, reduced the PSA from approximately 400 to 5.7! I am feeling MUCH better and functioning MUCH more normally.