Hi Lee and Ed had my first Denosumab (Xgeva) on Friday for bone mets following breast cancer 14 years ago. Feeling tired and pain in ribs and back horrendous but hoping it will help soon.  Some of side effects sound awful but hoping we can all avoid these!  Good luck with yours 

Hi Cosmopolitan

You Lee and me have had a good run comparativly in that we have survived 10+ years from our original cancer. But it is now back and causing us grief with pain and risk of bone fractures. Hopefully the Denosumab can give us some protection. I have the first injection next week. Where did the nurse give your injection? Thigh or stomach was mentioned but they did not say which. Post back to say how you are getting on and how well you are tolerating the Denosumab. Wishing you and everyone on this forum some respite from this awful disease.

Ed

Hi Cosmopolitan and Ed.

I had my fifth denosumab injection on Friday.  I always have it in the stomach it is just easier to access than dropping your trousers (ha ha).  It only hurts a bit not much.  No side effects so far.  I hope it helps as I am so scared of damaging my back really dont want to end up in a wheelchair.  I find that keeping active helps me more than anything.  I go walking my four dogs in the woods near where we live everyday for about 1hr45mins.  When I sit still for long it seizes up and I get sore and stiff.  I have an electric heat pad on the couch when I sit down and watch TV at night, which helps enormously.  Good luck both of you .

Lee x

Hi Lee

Thank you for your posts they have given me a great deal of support and hope. Especially that you are tolerating Denosumab well. One of the possible but infrequent side effects is osteonecrosis of the jaw bone. I am at a higher risk of this due to receiving radiotherapy to the jaw 10 years ago. Ive had the dental checkup and good to go with the proviso that any future extractions are carried out at the hospital.

I agree that excercise is good for everything to do with cancer and your long walk each day with your dogs must bring you joy. Settle anxiety and keep you fit. Ditto for me doing some work each day. It stops me dwelling on dark thoughts keeps me fit and helps me sleep a bit better at night. I too find sitting painful so thank you for the tip on using a heat pad. All the best

Ed

Thanks Ed.  Nice to hear from

you.  Mine was in the tummy and will be monthly.   Tiredness is a big thing especially for me who is used to being on the go all The time.  Perhaps a bit too much at times!!!  Also have nausea but hopefully the pain will subside.   Good luck with yours and let us know how you get on.  Enjoy your Sunday 

Thanks Ed.  Nice to hear from

you.  Mine was in the tummy and will be monthly.   Tiredness is a big thing especially for me who is used to being on the go all The time.  Perhaps a bit too much at times!!!  Also have nausea but hopefully the pain will subside.   Good luck with yours and let us know how you get on.  Enjoy your Sunday