Anyone receiving Denosumab XGEVA

Is anyone here receiving Denosumab XGEVA for metastatic bone cancer

Ive been advised to have this by injection  to slow the progression of the cancer and prevent bone fractures.

Id like to know how well it is tolerated and what side effects you have experienced.

Thanks in advance

Ed

Parents
  • Hi Ed,  I have the denosumab injection every four weeks in my stomach.  I have metastatic breast cancer with mets in pelvis, spine, ribs, skull etc.  I cant say I have had any side effects from this injection.  I have some side effects of fatigue and really bad rash (like I see you have from another post).  But I dont think it is from the injections, probably the other medication.  When are you starting, good luck.

    Lee

  • Hi Lee

    Thank you for your reassuring post on Denosumab. As usual there is a long list of side effects so it is good to get real life feedback from somebody receiving the treatment. Like you a recent scan showed up mets in multiple locations. I start Denosumab in 2 weeks time alongside immunotherapy.  Thank you for taking your time to reply and I wish you the best with dealing with this awful disease.

    Ed

Reply
  • Hi Lee

    Thank you for your reassuring post on Denosumab. As usual there is a long list of side effects so it is good to get real life feedback from somebody receiving the treatment. Like you a recent scan showed up mets in multiple locations. I start Denosumab in 2 weeks time alongside immunotherapy.  Thank you for taking your time to reply and I wish you the best with dealing with this awful disease.

    Ed

Children
  • Hi Ed,  yes good luck to you as well.  As you say it is a c---p disease.  I am trying to take one day at a time.  I was only diagnosed in September 24 so relatively new for me.  Are you in pain with you mets?

    Lee x

  • Hi Lee

    Had advanced skin cancer a long time only recently diagnosed with bone mets. My back and pelvis hurt and it is difficult to sleep ccomfortably but not in severe pain.

    Ed

  • Hi Ed I had cancer twelve years ago and came back last year with the bone mets.  My back hurts too but I manage the pain with tramadol and cyclizine as tramadol makes me feel sick.  Doctor prescribed morphine but I dont want to take it until I really have to because I tried it and it didnt agree with me.  Are you on the Macmillan forum there is one for Incureable cancer patients only.  There are so many positive inspirational people on there and very supportive.  Being nosy here, but are you really a farmer? :) 

    Lee x

  • I agree both tramadol and morphine make me feel sick plus constipated. I also like to have a clear head and not spend the day doped up. I will put off the day as long as possible. Thanks for the pointer to McMillan Ill take a look. Yes I really am a farmer retired but still working a little as it is a way of life rather than a job. Plus it is good for my mental health to be out doing something I enjoy in the fresh air. Hope you are keeping your pain under control.

    Ed