Abiraterone for Prostate cancer

It is very saddening to hear that the NHS have decided not to make abiraterone available to men with prostate cancer. Not only do we poor chaps not get screened but when the worst happens drugs which might help are not available.

what is all the more disturbing is this drug was developed by cruk scientists. It raises the question about the point of giving money for research for the fruits of that research only to be sold off to the highest bidder drugs company for it only to be sold back to the NHS at such a high price that they will not pay for it! How many more drugs do cruk have in the pipeline which will be following the same fate? We run, have tea parties, jump from aeroplanes to raise money in the expectation that the fruits will go to cure our loved ones not to line the pockets of a large drug company. 

Are we just wasting our time and money CRUk? Are we better off just leaving the research to big pharmaceutical companies and cutting out the middleman?

  • Hi Graeme-m,

    Welcome to Cancer Chat. Thank you for your post and sharing your concerns. We just wanted to let you know that we have passed your concerns and questions on to the most appropriate team, and we will update you with their response as soon as we can.

    Best wishes,

    Ben
    Cancer Chat Moderator

  • Hi Graeme, Abiraterone is available on the NHS, I'm not sure all trusts recommend it's use, but I have a few friends either on it, or had it but never after chemotherapy.

    Eddie

  • Hello Graeme-m,

    The Science team wanted to pass on their response to your post. Please see below: 

    "At the moment, abiraterone is available for men with advanced prostate cancer in England and Northern Ireland and men with high-risk prostate cancer in Scotland and Wales.

    Taking a new drug all the way from an idea in a lab to patients costs millions of pounds. We have to work with pharmaceutical companies and combine expertise and resources in order to get the lifesaving discoveries developed by our scientists into the hands of cancer doctors and patients.

    Once our researchers have identified a promising new drug in the lab, we provide the expertise, infrastructure and funding to help our researchers take this drug through the necessary lab testing and into ‘first in man’ clinical trials. These ‘first in man’ trials involve a small number of patients. However, due to the enormous cost and resource implications, we need the pharmaceutical industry to take promising new drugs further into large-scale trials.

    We simply can’t afford to run large-scale drug manufacturing facilities or pay the multi-million pound costs required to take new treatments all the way through late-stage clinical trials and legal regulatory processes. It certainly wouldn’t be an effective use of our supporters’ donations to effectively set ourselves up as a pharma company.

    New drugs must go through these rigorous clinical trials to ensure they are safe and effective. It is then down to the National Institute for Health and Care Excellence (NICE) to decide whether the drug becomes available on the NHS.

    NICE weigh up the benefits of a new treatment against its cost, compare this to what’s already offered by the NHS, and make recommendations on whether they consider the new treatment ‘value for money’. We’ve written a lot about the politics and economics of cancer drugs, and the need for a system that properly reflects cancer patients’ needs. 

    Regarding screening for prostate cancer, there is currently no national screening program because the only current option, the prostate-specific antigen (PSA) test, is not accurate enough. We helped fund a study (called BARCODE1) to develop a new saliva test for identifying men at high risk of prostate cancer. This saliva test is now being analysed alongside other potential screening options as part of the ongoing TRANSFORM trial, which aims to find the best way to screen men for prostate cancer."

    Moderator Anastasia