Has anyone had a mental health decline from chemo being combined with immunotherapy?

Hi, has anyone anyone else experienced a massive mental decline following Carboplatin, Paclitaxel and EC chemo combined with Pembrolizumab immunotherapy?

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  • Hello Flossyanne,

    Welcome to Cancer Chat and I'm sure members in a similar situation can reach out to you.

    If you'd like more information on the side effects of cancer drugs and advice on coping, you can look here

    I hope this helps,

    Moderator Anastasia

  • My husband was diagnosed with stage 3 lung cancer last October 2023. He was give chemotherapy Paclitaxel and Carboplatin for 4 cycles every 3 weeks. The tumour started to shrink and he was doing really well, then the oncologist decided to put him on Immune therapy every 6 weeks. After 4 sessions he got inflammation and blood clots on both lungs so they had to stop the immune therapy.
    what they didn’t tell us is that sometimes immmune therapy can cause this inflammation on a good percentage of people.  they put him on a high dose of steroids 16 a day to get rid of this inflammation. After suffering really bad side effects coming off the steroids for 8 days being sick and shaking (like a drug addict) they Have now after 6 months started a different chemotherapy called Docetaxel which is a strong one and at the moment he is bedridden and feeling very sick after just one session.  Has anyone else gone through this or is going through this treatment.? He has tried to remain positive but his mental health is declining now as the treatment does state that this can cause suicidal thoughts. I do my utmost best to keep him positive at all times and I often cry alone outside so that he doesn’t hear me. It’s hard and I feel very isolated all the time as my family lives 500 miles away and people who are my neighbours seem to have turned their backs on us and don’t keep in touch anymore. Please stay strong and know that other people are having the same emotions and try to stay positive.  Love and healing to you x

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  • My husband was diagnosed with stage 3 lung cancer last October 2023. He was give chemotherapy Paclitaxel and Carboplatin for 4 cycles every 3 weeks. The tumour started to shrink and he was doing really well, then the oncologist decided to put him on Immune therapy every 6 weeks. After 4 sessions he got inflammation and blood clots on both lungs so they had to stop the immune therapy.
    what they didn’t tell us is that sometimes immmune therapy can cause this inflammation on a good percentage of people.  they put him on a high dose of steroids 16 a day to get rid of this inflammation. After suffering really bad side effects coming off the steroids for 8 days being sick and shaking (like a drug addict) they Have now after 6 months started a different chemotherapy called Docetaxel which is a strong one and at the moment he is bedridden and feeling very sick after just one session.  Has anyone else gone through this or is going through this treatment.? He has tried to remain positive but his mental health is declining now as the treatment does state that this can cause suicidal thoughts. I do my utmost best to keep him positive at all times and I often cry alone outside so that he doesn’t hear me. It’s hard and I feel very isolated all the time as my family lives 500 miles away and people who are my neighbours seem to have turned their backs on us and don’t keep in touch anymore. Please stay strong and know that other people are having the same emotions and try to stay positive.  Love and healing to you x

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