I've recently been taken off Tamoxifen (due to a dreadful reaction)  and put on Letrozole and monthly injections of Zoladex. I'm about 3 weeks into the Letrozole and my head has started to itch like crazy. It's unbearable. There's a slight rash that's on my neck and I'm sure I can feel a rash in my scalp too. My head feels like it's on fire and I just want to scratch my scalp constantly. It's so miserable especially at night.... I've heard that this could be a side effect of Letrozole. Does anyone else have this and what can you do about it? I want to change brand of Letrozole and see if that makes a difference, but I'm not sure if that's possible. I'm waiting for the doctor to call me back torture but just thought  I would ask on here and see if anyone else had any advice? Thanks in Advance