Hi Moggymad62

I had a hellish time on tamoxifen and was delighted to move onto anastrozole. The only side effect on anastrozole has been hot flushes but these have been reduced via 'sertraline' an antidepressant that GP prescribed.  You don't have you put up with side effects, there is medication available to manage them. 

Hi Magpiemaggie, thanks for replying to my post. Since I made the switch from letrozole to anastrozole just 6 days ago my joint pain has miraculously disappeared. Whether this is permanent or not remains to be seen but for now I am pain free. Did you notice improvements as quickly? I'd love to know if it's possible for it to have worked so fast and it's not just a temporary lessening of my wrist pain that may have happened anyway. I guess time will tell. I am also just starting on venlafaxine to help with the hot flushes and night sweats which have definately not been affected by the switch and are as bad as ever. Hoping the new anti depressant will help, just need to give it time as I have to increase the dose gradually. Hope you are OK, love and hugs, Mog

Hi Magpiemaggie, thanks for replying to my post. Since I made the switch from letrozole to anastrozole just 6 days ago my joint pain has miraculously disappeared. Whether this is permanent or not remains to be seen but for now I am pain free. Did you notice improvements as quickly? I'd love to know if it's possible for it to have worked so fast and it's not just a temporary lessening of my wrist pain that may have happened anyway. I guess time will tell. I am also just starting on venlafaxine to help with the hot flushes and night sweats which have definately not been affected by the switch and are as bad as ever. Hoping the new anti depressant will help, just need to give it time as I have to increase the dose gradually. Hope you are OK, love and hugs, Mog