After having breast cancer in 2008, chemo, lumpectomy, radio, herceptin for a year, I then had tamoxifen for almost 10 years, it returned in 2019. Had various treatments, now on Tdm1(kadcyla) but have recently been diagnosed with cirrhosis of the liver which is likely due to the tamoxifen. I may have to come off the Tdm1 as this can also damage the liver so alternative is to find a trial.. Would love to hear from anyone who has this as I stupidly didn't realise how serious this is.