Hi Peter, and a warm welcome from me, As Moderator Lucie has said, I have some experience of prostate cancer PCa and treatments, diagnosed over 3 years ago,, with spread to lymph nodes and 4 organs, so had hormone therapy HT, from the beginning and radiotherapy RT, "4 weeks,"10 months into HT treatment, which is/was a standard treatment at the time, for advanced prostate cancer APCa, for the vast majority of people, treatments have moved on since then, so I'm a little unsure why your options are either HT or RT, would you be ok sharing your cancer stats, PSA, Gleason score and TNM staging, and how many lymph nodes are cancerous, as for side effects, almost everyone gets them to some degree, fatigue is familiar to almost everyone, but it's impossible to say who, and how hard, anyone will be hit by them, but there are many ways to treat almost all of them, but as to which option to choose that is your choice my friend, as a very general rule HT side effects tend to last to some degree, unless treatable, all the time your on them, RT side effects are fewer, but more severe.

Eddie 

Hi Peter, and a warm welcome from me, As Moderator Lucie has said, I have some experience of prostate cancer PCa and treatments, diagnosed over 3 years ago,, with spread to lymph nodes and 4 organs, so had hormone therapy HT, from the beginning and radiotherapy RT, "4 weeks,"10 months into HT treatment, which is/was a standard treatment at the time, for advanced prostate cancer APCa, for the vast majority of people, treatments have moved on since then, so I'm a little unsure why your options are either HT or RT, would you be ok sharing your cancer stats, PSA, Gleason score and TNM staging, and how many lymph nodes are cancerous, as for side effects, almost everyone gets them to some degree, fatigue is familiar to almost everyone, but it's impossible to say who, and how hard, anyone will be hit by them, but there are many ways to treat almost all of them, but as to which option to choose that is your choice my friend, as a very general rule HT side effects tend to last to some degree, unless treatable, all the time your on them, RT side effects are fewer, but more severe.

Eddie