Aggressive prostate cancer and radiotherapy side effects

After a year on hormone treatment and a TURP to improve bladder flow I will be starting radiotherapy next month. I have a choice of 4 weeks standard radiotherapy and I have read up on the side effects. I am told I have aggressive prostate cancer and as after a year my PSA is still high at 1.8 I am also offered a more aggressive form of radiotherapy which will target not only the prostate but the area immediately surrounding the prostate. I am told this procedure in still under review and its value not yet fully understood. The side effects however are a lot worse than for the standard radiotherapy. At age 75 my Consultant is of two minds whether the largely unproven benefits are worth the increased side effects. Has anyone had this more aggressive form of radiotherapy and can help me understand the side effects. 

  • Hi Clyde21, and a warm welcome to the forum, though I'm so sorry you have to be here, I was in the same place you are now 2 years ago, I too had been on hormone therapy and had a TURP, just before radiotherapy, I  had advanced prostate cancer in 5 organs and 8 lymph nodes, so the whole lower pelvic area was targeted with a much larger dose of radiation than is usually delivered. PS, I was 57yo at the time. 

    The benefits were, for me, my cancer was undetectable in all organs, and 7 of the nodes, so results were amazing, my friend I was never curable, but it's given me more time.

    The disadvantages,for me, " we are all different,', and many of my side effects are familiar to many, but as my cancer was in my bladder, bowels and rectum, they were targeted, and 2 years on I still have minor issues with peeing and pooing, though they don't limit me, and I've developed osteoporosis and  spinal stenosis, but whether all of these are treatment related I don't know, I would suggest you talk to your team about bone supplements, as radiotherapy can weaken the bones, and if you can get a little fitter this will help with the fatigue, which is very common, but always talk to your team, about any concerns or side effects, and my best wishes with your treatment 

    Eddie 

  • Offline in reply to eddiel

    You have had a terrible time. My cancer has not yet spread from the prostate but the Consultant thinks it will, even after radiotherapy, as it is some sort of aggressive cancer. He is concerned about my age (75) and ability to cope suggesting standard (as opposed to aggressive) radiotherapy might be best. You are coping well which is encouraging to me.

  • Offline in reply to Clyde21

    Hi Clyde, many prostate cancers have the potential to evolve into a more aggressive variant, but that yours is still contained is good news, you could ask him about brachytherapy, it may be an option and generally comes with fewer side effects, was surgery ever talked about?.

    Eddie 

  • Offline in reply to eddiel

    Hi eddiel. I will ask about brachytherapy although it was never suggested. I was told surgery was not an option. Did not discuss at the time. Was still taking it all in. I can ask again. Regards

  • Offline in reply to Clyde21

    Hi Clyde, Brachytherapy isn't available at every hospital, but like any treatment, if your hospital doesn't do it, you can be transferred to one that does, and remember there's no such thing as a stupid question, only not asking it. you can ask for a full copy of all consultations and scans, or ask if you can record the meeting on your phone, taking someone with you is really helpful as well

    Eddie