Enzalutomide has stopped worķing and I am seeking advice on whether to switch to chemo or radium 233 or to do nothi ng.  My main aim is to minimise discomfort rather than to extend my life.  The cancer has spread to my spine.  It is not in my lymph nodes. I am hoping that radium 233 will minimise bone pain.

In fact my main discomfort at the moment is constipation and none of the laxatives I use sre very effective.  I am also lacking in energy and can only walk aut a mile, whereas a year ago I would regularly walk 6 or 7 miles