Oesophageal cancer

Hi,

My husband was diagnosed with oesophageal cancer T3, N3, M1 - it is at the junction of oesophagus/stomach and has spread.  Since diagnosis, we have been having HCX chemo, 6 cycles.  I wanted to ask [@davek]‍ a question (apologies I can't see a way of sending a pm via this site).  I read your bio with interest as your diagnosis seemed the same as ours, we were also told surgery was not an option due to spread.  I wanted to know :

1) How many cycles of chemo did you have in total, and was it EOX the whole time?

2) After you had your scan and were told that both primary and secondary had reduced in size, were you told to have more chemo but you decided not to, or did the doctors tell you to stop and just have scans every 6 months?  We had a scan after cycle 4 and were told that both the primary and other tumors had reduced in size, we are about to do cycle 6 and I am hoping for good news after that but understand this is rare, your story gives me some hope.

3) Were you offered / would you recommend clinical trials with immunotherapy? We haven't been offered anything but I found one through searching, will discuss with oncologist but wanted to ask here too.

Any help or advice is much appreciated, thank you

 

  • Hi,

    If you want to private message someone just click on their username and send a friends request.

    Meanwhile:-

    1) I had four cycles of EOX - originally six cycles were suggested but new research at the times indicated that outcomes were slightly better after four as the immune system recovered more quickly than after six. The scan after cycle 4 showed that the tumours had shrunk by between 40% and 60%.

    2) I was told in no uncertain terms that my partial remission would probably be temporary so I should enjoy the time I had. I was put on watch and wait with six monthly CT scans - this was a compromise as my oncologist suggested 12 monthly but as I'd had no obvious symptoms I insisted on more frequent scans.

    3) at the time the nearest to immunology trials available was Herceptin but I was HER2 negative. If I slip out of remission I would be actively chasing immunology clinical trials. I assume you've checked out the CRUK database at www.cancerresearchuk.org/.../clinical-trials-search

    I hope this helps.

    Dave 

     

     

     

  • Hi, my husband has the same cancer which has spread to his liver. Diagnosed in April 2019. He had a full course of eox which finished November, oesophagus tumor shrank down and he was feeling good but unfortunately a scan showed new tumors growing in liver so although we were expecting a break we are straight onto new treatment, he tested positive for her2 so has started herceptin, not free for us as we live in nz so $4100 every 3 weeks!  will find out in a few weeks if it has done anything, if do we may be moving back to UK where it is free! has he had a test for her2? Apparently if u are positive the cancer is very aggressive so not necessarily a good thing! They say immunotherapy is the way to tray cancer the best but in nz only used for melanoma,  not sure about uk but worth finding out got sure