Hello, I just wondered if anyone has experience of anyone with Non Hodgkin's DLBCL, my brother, 54, was diagnosed in August, he's on 4th cycle of R-CHOP chemo. The lymphoma has transformed from indolent to aggressive. He is very ill, is having several lots of blood transfusions after each treatment, breathless and exhausted all the time. He literally struggles to stand up. I don't know if this is normal; he is so poorly and we're so worried. It would be lovely to hear from anyone who's supporting someone going through the same or similar. Thank you.