Hi Martin You need to allow your wife to take the lead on this but you also need to be ready to support her what ever way she needs. It could be she does not want to have to worry about you as well - I know this sounds weird but she may be concerned about your reaction. I don't mean to be insulting but how did you actually offer to go with her. If it was " I can take time off if you want/like" then her reaction could be no its ok. Perhaps if you really want to go especially on her first treatment you could phrase it more like " I would really like to take you and be with you for the first one at least" If she still says no then accept it. Me I wanted my husband there and he was (we had taken early retirement so work was not a worry) but my treatment took at least 5 hours so no way could I have got myself home. Also he knew what went on so I did not have to explain . Good luck