Stage 4 melanoma

My partner was diagnosed with Stage 3 Melanoma in 2019 with an unknown primary. He had a radical neck dissection and a year on targeted treatment. He was clear up until April last year, it had come back but in his liver and leg. He was put on ipi/nivo but only managed 3 doses before spending a month in hospital due to hepatitis toxicity. He then went back onto targeted drug therapy but unfortunately this stopped working 3 months ago. He then went onto opdualag immunotherapy and it seemed a promising new drug. 4th treatment and his scan results show it has not helped and the tumours continue to grow. The only option now is clinical trials and the complete unknown. He was early thirties when this started and I am just hitting 30. 

Does anyone have any information on what to expect with clinical trials? 

Parents
  • No knowledge of trials as pembrolizumab is working for my partner. He's stage 4, had a radical neck dissection only to find out it was already stage 4 after biopsies on another area during the op showed it had travelled there. It's horrible. I'm sorry your partner is going through it so young. It's really not fair. Someone at the dermatology waiting room recognised my partner's scar and guessed his diagnosis then showed his own. It's a *** club to be a member of.

Reply
  • No knowledge of trials as pembrolizumab is working for my partner. He's stage 4, had a radical neck dissection only to find out it was already stage 4 after biopsies on another area during the op showed it had travelled there. It's horrible. I'm sorry your partner is going through it so young. It's really not fair. Someone at the dermatology waiting room recognised my partner's scar and guessed his diagnosis then showed his own. It's a *** club to be a member of.

Children