Hello and thanks for posting,

You asked about skin discolouration around your PICC line. This does happen, and can vary from individual to individual patient.

It can be a localised effect for the surrounding skin from the drugs being given into the veins. There can be a reaction in the small blood vessels and capillaries from increased use of the veins having drugs through them. It will probably persist for the duration of the treatment, and should fade slowly as treatment ends. Some people just have different skin and vein composition which makes this more likely to occur.

I hope this helps.

Best wishes,

Vanda