I thought my case was simple. Symptomless PC confined within the capsule. My treatment plan is 6 months of HT followed by external beam RT this coming October 2024. I am 73, fit and active. Simples ! However on my second month of Zoladex the side effects are kicking in. Hot flashes and severe pain centred on my upper arms, shoulders and upper back ONLY AT NIGHT? I cannot distinguish whether it is muscular, joint or God forbid in the bones. I suspect it may be a drainage cause only happening whilst lying prostrate (excuse the pun) This obviously wrecks my sleep. I find myself wandering around the house, moving from bedroom to bedroom to lounge in search of the right temperature and a comfortable support. Low level depression is kicking in. Strangely, once up and moving, it all goes away until the next night. My Oncologist has suggested pain killers. I take standard Ibuprofen and Paracetamol which is mostly ineffective. Does anybody recognise this stuff? Can anybody offer any help. Please.