Chemo or not?

My husband is 73 and really fit.  He has recently had surgery for stage 3 colon cancer and had it removed without any need for a colostomy bag.  He had 21 lymph nodes removed and the first lymph node had cancer cells but the others were clear. T3N1.

Apparently he is missing a Miss Match Repair gene which is the cause of his cancer, isolated to the bowel.  

The oncologist is telling us that he has a 70% of the cancer NOT returning but if he has 4 rounds of chemo  oxaliplatin and capecitabine this will increase to 80%.  My husband has recovered really well from the surgery and is feeling good.  He is not sure that the possible long term side effects are worth the 10% benefit.  He is very stoic and is not worried about short term sickness .

i think we were both expecting to get a better protection from the chemo.  I really don’t know what to think.  

Is immunotherapy a treatment at this point?  Is it less toxic?

Any advice would be greatly appreciated.

Thanks 

LindaLou

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  • Hi LindaLou2 and thank you for your post,

    I am sorry to learn that your husband has bowel cancer. This must be a difficult time for you both.

    It can be hard trying to make sense of what is happening and having to make a treatment decision. You may have seen this already but Macmillan Cancer Support has some helpful tips on deciding on treatment. When making decisions like this, there is not always a clear right or wrong answer. It is also difficult because no one can say for sure how the treatment may affect your husband. It is this uncertainty that can make it hard to decide. 

    Chemotherapy is one of the main treatments that is given after surgery. Immunotherapy is mainly used in the treatment of bowel cancer that is advanced (the cancer has spread to other parts of the body). Immunotherapy is given depending on what treatment a person has had before, what type of genetic changes are seen in the cancer cells, and how far the cancer has spread. It is not generally used in your husband's situation.

    If your husband is struggling to make a decision it might be worth having a chat again with the oncologist if possible, or nurse specialist (CNS) if he has one, particularly as they are involved in his care and know his situation.

    I hope this helps a little Please get back to us if you need any more information or support.  You may find it helpful to talk things through with one of the nurses on our helpline.  The number to call is Freephone 0808 800 4040 and the lines are open from 9am till 5pm Monday to Friday.

    Take care, all the best,

    Jemma

  • Thank you Jemma this is very helpful. 

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