Scared this is something like PC

Scared this is Cancer

Apologies for the long post, im trying to be very thorough.


Some background:

27M.

weight 85kg - was 122kg around this time last year.

Height: 6'2"

Current medications:

Amplodipine - 5mg daily.

Certlizumab Pegol - 40mg 1x every 2 weeks. 

Nexium ppi - 20mg daily.

pre-existing conditions:

Ankylosing spondylitis - 10+ yrs.

Psoriatic Arthritis - 10+ yrs.

Arachnoid cyst on brain - not sure if relevant, found years ago when a previous arthritis drug was giving me headaches. 

Started the Amlodipine around December when I went for routine bloods and it was noticed my BP was quite high. Turns out that my sister and father have high BP so I'm attributing this to genetic. 

Familial history of cancer - mother treated for triple negative breast cancer. 

around 2, 2.5 months ago I started getting quite a sore throat. I go back and forth the GPs with it and they prescribe me phenoxymethylpenicillin around a month ago This didn't really solve it.  The perscribed me the PPI around 3 weeks ago. I decided to discontinue the mounjaro (2.5mg the entire time) around three weeks ago as I've decided I have lost enough weight. 

around 3 weeks ago, I started getting bloated off small amounts of food. Didn't notice any change in bowel habits at the time. Didn't particularly want to eat, attributed this to the mounjaro changing my eating habits as I was used to eating like a lizard with OMAD. At the same time, I noticed my teeth looked quite decayed. Jump to a few days later I notice a stool had black lumps in it whilst in the airport, which was concerning. This continued when I landed at the location. I felt the same in regards to food, was full off tiny amounts but attributed that to eating very little on mounjaro for the past year. I was also feeling pretty tired. Not like collapse tired (As I think I walked quite a few miles that day 5+), but more tired than usual, like sleep wasn't restorative and I could easily sleep all day if I wanted. I then have a pee which was quite dark in color two days in (now I attribute this to dehydration) but this and the other symptoms prompted me to check myself into hospital as this was very strange. 

A CT of the abdomen and the throat were taken, no contrast. the following day, a nasopharyngolarynoscopy, an colonoscopy and a oesophago-gastro-dudenoscopy was done. The results of the CTs were as follows (abdomen):

Liver - unremarkable and smooth outline. no gross intrahepatic lesion detected.

Bilateral intrahepatic ducts and common bile ducts not dialated. 

Pancreas - normal in size. No focal mass lesion is noted in the pancreatic parenchyma. Main pancreatic duct is not dilated. 

Spleen - Normal in size, no focal lesion is noted in the spelic parenchyma.

Gallbladder - appears normal. no hyperdense gallstone noted. no abnormal wall thickening or pericholecystic collection seen. 

Bilateral kidneys normal in size. 1.3cm hypodense lesion with rim calcification in power pole of left kidney, may represent cycst. No other focal mass lesion is noted in bilateral kidneys. A 0.3cm stone is seen in upper pole of left kidney, no other hyperdense renal or ureteric stone is noted, no hypdronephrosis or hydroureter is seen bilaterally.

both adrenal glands not enlarged, nno definite adrenal mass is noted.

No gross obstructurive mural mass or abnormal dilation is noted in bowel loops. a few iverticuli are noted over sigmoid colon. Nopericolonic soft tissue stranding is seen. No abonrlam dilated appendix is seen. No pneumoperitoneum is noted.

Urinary bladder unremarkable. - with no focal mass lesion or hyper dense intravesical stone seen. prostate gland and seminal vsciates are unremarkable. No enlarged (>1cm) abdominal or pelvic lymph node is seen no focal pelvic mass noted. there is no ascites.

Mild subsegmantal pulmonary atelectasis is seen over bilateral lung bases. no plueral effusion is evident. 

Mild lumbar scoliosis with convexity towards left side is noted. No vertebral collapse. No destructive bone lesion noted. 

Throat:

2cm x 0.8cm x 2cm(CC X AP x TS) ill circumscribed hypodense lesion is seen over the base of the tongue around the pre epilottic region. A few small calficiation and gas densities within. features are nons-ecific in nature, with possibilities include retained secretion, inflammatory/ineffective changes or less likely neoplasm. suggest clinical correlation with endoscopy finding for further evaluation.

Both tonsils prominent with no gross mass or fluid collection noted.

Both thyroid lobes are normal in size. No focal thyroid nodule is noted.

Shotty bilateral cervical lymph nodes are noted, measuring up to 0.6cm in short axis over left cervical level II, probably reactive in nature.

No significantly enlarged supraclavicular lymph node is noted.

Mucosal thickening is seen in bilateral maxillary and bilateral ethmoid sinuses, could represent retention / mild sinusitis changes. The rest of paranasal sinuses are clear.

Left fossa of Rosenmuller is mildly obliterated by soft tissue swelling, may represent inflammatory changes. Suggest clinical correlation with endoscopy finding for further evaluation. 

No focal mass lesion is otherwise noted in the rest of the naso - and oropharynx. No significant otomastoid effusion is seen.

The parapharyngeal spaces are well preserved. No abnormal mass lesions noted in bilateral masticator. Parotid and carotid spaces.

No focal mass lesion noted within oral cavity, the sublingual and submandibular spaces are unremarkable. 

no abnormal soft tissue densities noted in preverterbral soft tissue spaces.

No focal lesion noted in the infrahyoid neck. 

The paraglottic space is clear. The pyriform sinuses, aryepiglottic folds and false cords are normal in contour. The true cords are symmeteral with no evidence of cord paralysis. no paralarygneal soft tissue mass is seen. 

No significant mass lesion is noted at the upper thoracic region including the thoracic outlet. 

Ooesophago-gastro-duodenoscopy results:

Indication: dyspepsia

Findings: scope to D2

duodendum: no ulcer. Mild duodenitis noted at D1.

Stomach: Empty, no ulcer seen. Antral gastritis noted. Clo test, antral biopsy taken. 2mm polyp noted at gastric body and fundus, removed with forceps for histology. 

Esophagus: no significant hitatus hernia or esophagitis seen 

diagnosis: Duodenitis, gastritis, polyp(s).

Colonoscopy results:

indication: Altered bowel habit.

findings: scope to terminal ileum, caecum and appendiceal orifice noted diverticuliu noted at caecum and ascending colon. no tumour, ulcer or significant polyp seen thorugh the examination.

minimal internal haemorrhoid noted.

Diagnosis: Diverticulum, haemorrhoid. 

nasopharyngolaryngoscopy Report

Indications: Sore throat, odynophagia

Findings: nasal cavity clear. Middle meatus clear. deviated nasal septum to right. Spenoethmoidal recess clear. Nasopharynx clear. Hypopharynx congested. Vallecular cyst. Vocal cords clear and mobile. Pyriform fossae clear. 

Diagnosis: pharyngitis, vallecular cyst. 

I have the results images from both CTs, the report images from the scopes and the videos of both CTs + each individual scan. After this, I was given some medicine, some anti biotics (amoxicillin IV + pills to go away with) which must've done something as my White count dropped to a level my doctors were happy with. I was subsequently discharged. Have not had any bowel movements with darkness in them since. 

Since then, I've had the following symptoms I'm quite concerned about:

Throat is nowhere near as sore as it was - its still slightly sore but it comes and goes in strength. right now it feels fine. 

I'm still getting a bit bloated after meals, but no where near the level I was. I can actually finish a meal now instead of a tiny plate. 

Weight loss - I'm noticing I've dropped a fair bit of weight the past couple of days without trying which is quite concerning, not sure this is a catch up of those two weeks of little eating + no gym (routine goer three times a week strength training - haven't been since the 13th) or something more ominous. 

Back pain - having some minor back pain.

abdominal pain - having some minor upper abdominal and lower (right side) abdominal pain. Not constant, comes and goes. Not that bad a pain, really quite minor but still rather concerning. occasionally on the left as well. 

Itching - had some brief itching for two days, think it was related to a bit of sunburn + psychosomatic from DR google.

Tiredness - still getting rather tired quite easily despite sleeping a full night. Also noticing tiredness after a meal. 

Of course these symptoms have me quite concerned and worried that its something like PC. I know that's very unlikely but I wanted some opinions on what to do next and what people's thoughts are. I'm praying its just what the diagnosed me with and nothing more serious. 

  • Apologies for the absolute wall of text. 

  • Should add that the biopsy on the polyps came back competely negative for anything bad. 

  • Hello Prayingfortheallclear, 

    So sorry for the delay in replying to you - I meant to respond to you earlier but somehow missed your post so sincere apologies for that. Thank you for sharing all the details of your story and it's no problem writing a long post and trying to be thorough. 

    It sounds like you have had reassuring results - it's good news for example that the biopsy of your polyps have come back fine. The fact that you had a colonoscopy and that nothing too serious was flagged is excellent news. 

    Unfortunately no one on here will have the medical expertise to tell you what it might be but I think it is important that you flag anything you are concerned about to your GP. In particular, as you mentioned you were taking the Mounjaro, this is something you need to mention to your doctor in case it had an effect on your bloating or any of the abdominal or other issues you experienced subsequently. 

    If you are still worried, it would not hurt to seek a second opinion and to talk to another GP about all the issues you have experienced recently. The medical experts will I am sure be able to explain everything that concerns you and hopefully give you the reassurance you need. I am certainly keeping everything crossed for you that it all turns out to be nothing of concern. 

    I also hope that you will hear the thoughts of other members of our community who have experienced similar symptoms in the past. 

    Best wishes, 

    Lucie, Cancer Chat Moderator