I am 55yrs old postmenopausal for10 years, been on HRT for 2 years. Recently I have had 2 episodes of PMB. TVUS showed 8.7mm endometrium heterogeneous and irregular margins. Pipelle biopsy is negative. Is it possible to miss the cancer/hyperplasia because pipelle biopsy is a blind biopsy. What if the sample taker has missed the abnormal area. What if the endometrium continues to thicken. If I am discharged by gynaecology (most likely) I will not be checked again. I don't know what I should do.