Hi 

I've recently been diagnosed with CLL (March) and chose to start chemo taking Acalabrutinib. After the initial few weeks of nausea things seemed to settle down. My glands went down and my energy levels improved. However, things seemed to be deteriorating and I'm tired, nauseous and have headaches all the time. Not knowing that extreme tiredness was a side effect of the drug I asked my Doctor why I was tired all the time, he said I shouldn't be and suggested I have a blood test for low iron. This test was not done and the next time I saw the Doctor I asked him directly was my tiredness a side effect of the medicine and he said no. He then said it could be the cancer and he would arrange for diabetes and thyroid test. When I investigated it is clear that extreme tiredness is a side effect, what I can't understand is why my doctor would not acknowledge this. Please, can I ask has anyone else experienced similar issues with this drug and what was the advice from your doctor. Any ideas why my doctor is not acknowledging the side effects. 
PS I will ask my doctor when I summon up the energy and courage  

PSS Any thing I can do to combat the tiredness