Does anyone know, or have any experience, of how long chemo starts to take effect? I had my first session last Thursday (and have it every Thursday now for about 20 weeks), but my breast cancer lump is getting bigger. It was 31mm, triple negative and grade 3, so I know it can grow abnormally fast, but it feels massive now; actually aches when I take my bra off, I'm guessing because of the extra weight? I'm just so worried about it growing quicker than the time it takes for the chemo to work. Don't know if I should phone the breast care nurses, not really sure what they would say.