Hiya I take letrazole, equivalent to tamoxafen.

It does effect your sleep pattern.

But it soon settles down.

I don't get mood swings.

I have been put back into the menapause because of it.

Hope this helps even a little.

Take it day by day 

Sending squishy hugs

Hi ann

thsnks so much for the reply. Much appreciated 

Hi 

I have started to take letazole about 16 days ago !! 

And I have trouble sleeping too 

First three days and three nights I didnt sleep At all  but after that it got bit better but still when go to bed feel restless then I come down and sleep on the sofa put TV on then eventually  manage to fall asleep!!

Also I have some other side effects my  legs and ankles hurts 

First thing in the morning it's fine no pain but after hour or so when start walking about then pain starts 

Then i put surgical stockings on pain goes away 

Also other side effect I have tingling feeling near my ear and one side of my head it's very annoying when I try to sleep !!

Also on my legs I get yellow spots and some places pink area , but it goes away after few days but cant see any swelling 

So I am bit worried about blood clots etc 

Did you or anyone else had these side effects ?

Jeet123

I've been taking it for over a year now, I nearly gave up because the pain in my muscles and bones was awful. Some days I was crawling, but after a month it calmed down, still get muscle pain etc but nothing like it was. It put me back into the menapause also. The sweats r god awful lol. But hey I'm here to tell the tale 

Hi

Thanks for your reply 

At the moment the pain is bearable I hope it doesn't get worse !! 

Also I am only having in legs and in ankles at the moment and it ease with stockings!  

I have been reading some reviews of this drug and mostly they complained having joint pain 

Well have to wait and see how it goes with the time 

Thanks again 

Hi there, I know this post is from January but I'm commenting anyway lol.

I was diagnosed with breast cancer in 2018, it had spread to the lymph nodes, I had surgery and treatment, and was also put on tamoxifen and zoladex, (still on both now) it's very difficult to get through to my oncologist during this pandemic, if I'm honest the hormone treatment has played havoc with my bones and joints (I'm only 45 now) and I have about a week a month that I just feel completely overwhelmed and exhausted, and tearful. 
bedn waiting for a bone density scan for months! Apparently we are supposed to have one at the start of hormone treatment but I never got one unfortunately, anyone had one of these? 
anyway, I hope everyone going through the rollercoaster of this horrid little "c" is doing well both mentally and physically.  
much love. Emma