My 50 year old wife has just been diagnosed with stage IV Adenocarcinoma (<3cm tumour on left lung) which has spread to the brain (6 mets known at present - MRI in two days).
We had our first meeting with the oncologist today who has recommended a combination of immunotherapy (Pembrolizumab/Keytruda) and chemo (Pemetrexed & carboplatin) initially for 3 months on a 21 day cycle, followed by targeted radiotherapy once it is established if the tumours are shrinking.
My question is what is the optimum timing / order of treatments - intuitively you'd think the radiotherapy should run concurrently with the immuno? Or is it better to let the immunotherapy to run its course before the radiotherapy?
Really appreciate any advice - I'm learning as fast as I can but appreciate any views please! Equally if you are aware of any emerging treatments that might be worth considering do please let me know - thank you.
