Starting CHP for stage IVb diffuse large B cell NHL soon

Polatuzamab vedotin

Clyclophosphemide

rituxamab

 

6 cycles over 18 weeks (1 cycle every 3 weeks)

 

has anyone had a similar treatment. What was the experience like? If you felt bad, did it last the whole 3 weeks of the cycle, or just a few days and you got a couple of weeks of relief until the next one. 
 

Everyone is different of course, but some expectation management might be helpful. 
 

having said that, if you had a really bad time I'm not sure I want to know that! My GI Dr said this want a bad treatment. I'm really hoping to hear from people who can confirm that..;)

 

Thank you

  • Hello.

    so for some context, 31, and I am 1 year in Remission from Burkitt Lymphoma - one of the rarest and most aggressive (albeit curable) forms of NHL. 
     

    FIRSTLY - take some hard boiled fruit sweets to the treatment with you!! Chemotherapy drugs leave abit of an awful taste in the mouth - trust me on this, it's probably my most useful piece of advice!

     

    I had heard a lot about DLBCL from my drs during the long diagnosis phase of my story, and in truth, my specialist said 'that would be the one I would choose, if I had to' - Alas, not to be for me after getting test results back!

    anyways, my story isn't your story, back to you - I don't think you should have too much reason to be too concerned over CHOP. I had one course of it (before being moved on to heavier stuff) -it took 4 hours, and the whole event itself was very uneventful at the time (but don't forget the sweets!) Of course everyone reacts differently, and adverse reactions do occur this you should bear in mind... also, hair loss is a given... sorry to let you know.

    when discussing my treatment options with my dr, she informed me that if chemotherapy had a scale of 1-10, R-CHOP would be a 1, and would be the most common option used for most, especially those older in age.

    I hope I've managed to help a little. In truth treatment can always have bad reactions however in my experience it wasn't so bad, and I think R-CHOP was considered the LEAST adverse in the chemo regimens available. My main issue aside from the hair loss was nausea, this lasted pretty consistently through the entire cycle (please ask the nurses there for some strong anti-sickness to take home with you)

     

    Sean

  • Thank you so much for your reply, and so sorry to hear you had to be moved to a tougher regime for a rare form. 
     

    actually, I am waiting for 1 stain result to comeback, and this is to check for 'double or triple stop' I think they call it, and if it does have this they may put me on a tougher regime that would mean me staying in hospital for about 4 months to knock it so that it never comes back! Hopefully this is unlikely, but it is possible, and as your case shows, rare things can happen...!

     

    That aside, I am 60, don't have that much hair left, and hair loss is the least of my worries I'm pleased to say. Thanks for your tips on the boiled sweets, and will def get some!

     

    I'm encouraged by your comments about R-CHOP, which tallies with what my GI Dr said. Thank you for that ;)

     

    the nausea not so much, but in the scheme of things, to get rid of this, I guess that's a small price to pay!!

     

    I'm so pleased to hear you're in remission. Long may that stay the way. Thank you so much for your reply, that's very encouraging. Although I'm 60 I have a 6 year old son (and 26 year old girls!) and the only thing that matters is I'm here for them as long as possible. 
     

    good luck and thank yo!

  • Hi that's not a problem at all I hope I've helped somewhat.

    Yes that sounds familiar - I was in for 6 months which at times wasn't the most pleasant experience, however always got to remember the end goal.

    you know where I am Now if you ever need to message me on here and chat