Hi , January isn’t such a long time ago to be completely over your surgery, so some of tiredness may be due to that. I experienced aching joints for about five months .That was bearable and did eventually subside. , With me it was more  loss of appetite then nausea , that too stopped. The terrible hot sweats, would not call them flushes, have been driving me crazy for four and a half years. So much only last week I called my Breast care nurse and said I want off Letrizol. Fortunately as I an  now low risk despite three primary tumours , the Consultant agreed. . 

Unlike others I would not take that risk if I was not so near to coming off the drug anyway as is the standard for my pathology. 

Stick with it it is saving your life. 

Hi Kay,

Thank you for your feedback. There have been a couple of times where I didn't think I could continue using this drug. I guess I just have to accept that my life cannot be lived as before but 5 years is an awful long journey to beat with these side affects!

Pleased that you are getting back to normal. Good luck!

x

I too have had 3 primary cancers, my first at the age of 32 and then again at 42 and again now at 63  and just finished chemotherapy for the 2nd time .. I have been prescribed Letrozole and only been taking it for 2 weeks and I have got terrible tinnitus .. the ringing in my ears at night is quite unbearable .. I have also started with hot flushes, which I haven't had for years since I had a total hysterectomy.   I have spoken to my Oncologist today who has suggested I stop taking the Letrozole for 2 weeks to see if it improves and if it does she will prescribe a different drug. ..

has anyone else had tinnitus with this drug ?

Hi Sharon

I’ve been on Letrozole since 2012, 8 years now. The first prescriptions I got from the hospital and felt fine but when I started getting them from my chemist I was obviously given a different brand as the side effects were awful. The main one being joints so stiff and painful, especially my knees, that I couldn’t get out of the bath without help. I did get hot flushes which were just about bearable. It was only by coming on this site that I found out different brands use different fillers in Letrozole which can affect how you feel. I had no idea Letrozole could be different! Apparently there are over a hundred brands. I tried a different brand (Sandoz) and the unbearable joint pain disappeared totally although I still got hot flushes. I now get Accord as Sandoz is discontinued. I was so tempted to stop taking them due to the pain which made me feel like an old woman, but so glad I tried a different brand which had an amazing difference. Please try a different brand as this will make all the difference to you once you find the right one. At the end of my 5 year period, the hospital recommended I continue with them for another 5 years as trials had shown it to be very worthwhile so I was happy to agree. My breast cancer has a reoccurrence period of up to 20 years so I’m not taking any chances by stopping it. Please don’t give up, try a different brand. The only thing that calmed my hot flushes was an antidepressant which is known to reduce them in some women. Good luck x