My partner is currently on Tamoxifen and is suffering with painful joints, bad sleep and loss of labido. I read on previous posts that Tamoxifen comes in different brands and that some brands give worse side effects than others. The brand Relon (Relonchem??) seems to give least side effects. I find it hard to believe that these days we still dont know enough about Tamoxifen in its different forms, and if there are alternatives. It seems a ridiculous catch 22 that either you have to put up with awful side effects, or not take it and run the risk of cance reoccuring. My partner stopped taking it for one day and immediately felt better but then naturally pannicked and went back on the Tamoxifen. Do we know if the binding agents in it can be a cause in different brands? Myn poor partner is tired, worn out, in pain and feels low and generally worn out. Luckily we have a strong relationship and i will back her whatever she needs or decides but why is a supposedly helpful medication so detrimental to her quality of life. Its like the lesser of two evils. I would gratefully appreciate any comments from sufferers and Oncologists for their knowledge and advice. Thank you