Hi all,

Going by the lack of replies, eye issues have not been documented in the Uk in relation to aromatise inhibitors such as Letrozole.

I have been taking Letrozole since August 2019 when I was diagnosed with breast cancer and apart from severe arthraglia have managed to keep fairly well. 
Unfortunately I precently developed Macular Eodema and am receiving a monthly injection in my eye. This is usually associated with diabetes but I am not diabetic so did some research and found that in the USA and Germany macular eodema is considered a very rare condition for non-diabetics but is associated with aromatise inhibitors. 
I have passed this information on to my local breast cancer clinic and oncologist and ophthalmologist and none had heard of it. Makes me wonder if professionals actually read relevant research papers.

Hope that you have fully recovered from your eye issues, mine are ongoing.

best regards

Phebie

Hi there,

I have developed pretty severe eye problems since using Letrozole. I was a little bit short sighted before, but could read fine.I was in such good nick before all this happened (even though I'm now 66). Now I struggle to read (especially with my left eye). This eye is also out-of-focus for distance, too. Very worried about any further detioration - as I'd then be , effectively, 'partially-sighted'. I am an artist and love to draw. Apart from the obvious 'inconvenience' (driving etc. - absolutely essential, as I live in the country now) this is devastating for me. The sight seems to be fluctuating a bit at the moment - just hope to god it'll improver or at least settle down - because, at the moment I cannot even get glasses to correct it. 

...Just done some further research - and found that aromatase inhibitors, including Letrozole, definitely CAN cause eye problems for some people (there have been quite a few studies on this). I've been referred to the county eye hospital for further tests by my local optician. I will let yoiu know how I get on...

Best to everyone,

Katie

How did you go on with your eyes? I am just starting Letrozole and I already have eye problems in the first place!

How did you go on with your eyes? I am just starting Letrozole and I already have eye problems in the first place!