Not sure how I should feel...

Hi Everyone,

So my mum was diagnosed with TNBC last July. Tumour was 5cm and 2 suspected positive lymph nodes. She completed 9 x PC chemo and 3 cycles of EC chemo. She had an MRI scan halfway through and the tumour (after 9 weekly PC) had only shrunk by 5 mm, which we were a bit upset about.

After chemo, she had a single mastectomy and full axillary node clearance.

Today we received the results from the pathology report, and the tumour was actually 6 cm, and 4/18 lymph nodes contained cancer.  80% of the tumour was dead, with 20% residual, and they got clear margins.

Not sure how to feel about these results. I'm thinking either they got the measurements of 5cm incorrect, or the tumour grew during EC chemo, and also spread to more lymph nodes?

I'm pleased about the clear margins, but also struggling to understand how the volume can decrease by 80%, but it can also grow at the same time?? all very confusing.

It has been suggested radiotherapy next for chest wall and collar bone, but no mention of Xeloda/Capecitabine…. and i'm not sure why, as I thought this was standard for residual?

Everyone I have spoken to have replied with a sorry/pity look on their face and I'm worried this does not provide a good outlook for the future.

Any advice/positive stories?

Thanks :) x

  • Hi Clare, 

    I've just completed chemotherapy and surgery for TNBC too. I'm sure they said to me that although scans can give an indication of size they don't know the exact size etc until they have it out and can look at it properly. 
     

    My pathology came back as 2.9cm left of a 5cm area that contained 2 tumours and my lymph nodes were clear but I'm also starting Radiotherapy to the full chest area on Friday. 
     

    I don't know if I've been any help sorry. Hopefully someone will come on who knows more about the Capecitabine as that has never been mentioned to me. 
     

    Hope your ok and your mum is making a good recovery after her op

     

    Sarah xx 

  • Hi Sarah,

    Thankyou very much for your reply.

    I did wonder if maybe the scan had been incorrect in original sizing, but then she had another one halfway through and they said it had shrunk from 50mm to 45mm, so could they have been wrong both times?

    My mum has a call with her oncologist next week, so will have to get her to explain further if she can.

    Hope you are recovering well from your treatment so far and I hope radiotherapy goes well for you on Friday xx