Abraxane and Paclitaxel( taxol drugs)

Hi I had  paxitaxol and it was awful  2nd one I.had allergic reaction to,so it was stopped .it caused me so much.pain  I had to.take morphine to cope. It was decided to stop that drug and to try  another taxol drug Abraxane.  I had that on Monday, and by wed I started to have few pains  and Thursday it got worse just like the paxitaxol that I.had, and I ended up taking morphine again.my fingertips are completly numb,I think.its caused me nerve damage  as I cant feel my fingertips and they feel.like they are burning when I touch them. I kept thinking tomorrow it may feel  better,but its now Sunday eve and they are still the same. Im going to call my chemotherapy team tomorrow, but im seriously thinking of stopping my trestmenrs, I only have 2 more to.go ,but I dont want my.fingers and feet to.get any worse and  be left with  permanently damaged hands or feet. Has anyone else experienced this, and if so did you continue with your trestmenrs and are you left with permanent damage to your hands and feet ,or did it go away eventually and if so.how long befote you felt normall again. 

  • Hi, 

    yep it all sounds very very familiar (:. I have it from wear and tear damage, BUT the reason I post is because my husband (oesophageal cancer) has just completed 4 cycles of FLOT chemo that includes a taxane (pixatel or something like that). He has experienced this sensation after every dose, numb finger tips, sparking ( like an electric shock) on the tips and incredibly sensitive to hot n cold. The good news is that after every treatment it went away. Gets worse for about a week after the 'dose' then gradually getting less as time went on. Now that the chemo has finished (for now) , he gets the odd 'spark', but about all.

    Stick with it if you can as I am told it is nuclear stuff that does the job

    best wishes.

  • Hilts.

    Thankyou for your reply

    I had Abraxane chemo last  Monday  and didnt experience my fingertips and pain in  both my hands till the Thursday,and im still experiencing these symptoms now  which are awful. I called my chemotherapy team and they got back to me and said " the taxol drugs can cause neuropathy  ( damage to nerves ) sometimes it goes away, so give it time and it may disappear  before my nxt treatments, but  to call if it gets any worse". They also said  it can cause permanent damage, and to try to stop that  my dose may need to be less nxt chemotherapy session  but to talk to my oncologist about it nxt time he calls.  But my worry is my grandsons friends mum has breast cancer like me  andvhad the taxol chemotherapy drugs lije me and a year on she still cant  feel.in one of her hands as it caused permanent damage. As mines in both my hands, im vety concerned ,and if it doesn't  rectify itself before my nxt treatments, im really considering stopping chemotherapy, as it was offerd as a precautionary mesure to try to stop my bresdt cancer returning in the future. Ive done 6 out iof eight ,the first four where EC chemotherapy, and they were ok.its the paxitaxol and Abraxane  ( Taxol drugs ) im having the problems with. Im due to.have Radiotherapy as well at some point,so im.thinkjng about quality of  life in the future ,as im.not sure if I want to risk getting permanent damage in my hands. My feet are also affected slightly,and even thty could end up worse ,which i really domt want.  I'll see if my fingers and hands improve and make my.decisions on that  and of course what my oncologist has to say.  Wishing your husband and you all the best. 

  • Blimey- what a choice.

    i don't envy you that dilemma.

    i suppose ultimately, no one can tell you for certain how the taxane treatment will pan out.

    it might or might not happen. Life really does throw in some awful choices.

     

    In saying that , I have had 'neuropathic' hands and feet for over 10 years (back injuries ): I cannot feel any of my toes and fingers frequently buzz, without sounding trite I still a manage to work full time and run around after the kids! I don't like it, it is very annoying,but there is nothing I can do about it.

    best wishes.