Anastrozole has ruined my bones.

Hi There

I was diagnosed with stage 2 Oestrogen positive Breast cancer in 2016. After just 3 round of chemo, my ping pong ball sixzed tumour had disappeared and the cancer had left my lymph noed. After 8 rounds a mammogram had showed that though I was clear, calcium depositis on my breast might flare up into cancer and so I had a full mastectomy of the right breast and had 14 nodes removed. The nodes came back clear and the breast was cancer free though I did have dome precancerous tissue. I had had a complete pathological response which considerably increased my odd of not having a recurrence, After some months I had my healthy breast reduced from an f to a c cup to match my new implant and the removed tissue was completely cancer free. I then began anastrzole with zoladex injections to stop my periods. I also took part in the palbocciclib trial from 5 cycles until it caused my to reject 2 implants and developed sepsis.  

After a year on Anastrozole a dexa scan showed that I had gone from moderate osteopenia -1.7 to osteoporosis -2.6. I was horrified. I asked the oncologist what my chances of recurrence were. She said 5 to 10% if I take the anastrozole and 7 to 10% if I take nothing.  So I stopped taking it. I worry that I have gone against my oncologist but if I keep taking that drug I reduce my chanced of recurrence by 2% but will definitely ruin my bones. I haven't told my oncologist yet

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  • did you have shoulder pain please and did you find anything to help it xxx

     

  • Dear Kibbles,

    I stayed on Anastrozole for two 1/2 years, I cannot describe to you the exhaustion and pain.  If you can swim, or some kind of excercise.  One person tried different brands of Anastrozole.

  • thanks for your advice i can swim but due to my disability i cant do it but at the moment its my shouders that are really bad with bone pain 

  • I remember and there wasn't anything I could do but rest, very, very tough....

  • Patsy here.

    I'm nipping into this conversation. I'm on Letrozole (same thing) I've had terrible pain in my shoulder, I ache all over, I shuffle.... and moan quite a lot.. The doctors have just sent me for a bone scan and I'm awaiting results. I came of the letrozole 3 weeks ago (don doesn't know) and the pain is receeding. I had breast cancer HER2 positive. Had a lumpectomy with clear margins. I have a choice: cancer coming back, or debilitating pain for the rest of my life with no cure. I'm on blood thinners, so I can't even take pain relief.

    Dear God, the cancer was bad enough but the treatment is sooooooooo agressive.

    Patsy

  • my oncolist has said i can come of

    the tablets and i have a 85 per cent the cancer wont return but the 15 per cent worries you dont it the bone pain is so bad im going to come off the tablets as have a few more bad side effects as well thanks for relying and the very best good luck

  • I hear you Kibbles, no one knows what it can feel like until they try it.  Each person must make their own decision.  I chose quality of life....hugs to you!

  • This is such a great site. I am walking more. Started back doing yoga twice a week. I am 63 before I stopped taking anastrazole I felt a lot older pain hips arm hand. So down would cry everyday.Live today tomorrow can look after ITS self.

  • I love it!!!!  We each intuit our own lives.  At 73, all insurance has been cleared, the process of reconstruction begins 3/25!!!!  My rt breast mastectomy was 12/12/14 and I did not need two breasts until now.  Cancer free, so many irons in the fire, I love my life....Tomorrow will take care of itself....

  • Im happy to see a positive on here, Id come looking for some tips about anastrazole, which oncologist gave me last week, on the Wednesday, Id started going down with what has turned into a monster chest infection, and because Im also on meds for Behcets disease I had to lay off my methtrexate as you cant take that with a chest infection, and Im on antibiotics.

    I wanted to get some feel for what its like to be on anastrazole as work expect me back from 17/2. Ive been feeling totally battered first by the dx in late October, then surgery 3/12, then chest infection late January. Im full of arthritis and have hip replacements, a mid foot fusion, and fused ankle, and my toes have all been unbuilt and rebuilt. I get horribly breathless due to Poland syndrome which means my rirbs go in instead of out, and frankly, Im wondering how the hell I will make it til 66 to get my OA pension (Im 61 and got medically retired from my former job 15 years ago, on a pension) I like my job, providing support for disabled uni students, but its a gig economy type post, it involves travelling by bus to varied locations, and lugging a laptop or pile of note papers around with me. and Im starting to wonder if Im up to it. already one of the other jobs I do there has pulled my bookings cos they are worried it would be too much for me to do a full day shift recruiting candidates, and I know they are right. it would atm.  but on top of all this, I have no idea of how to pace myself., Ive been on heavy duty steroids and methotrexate for the last 17 years, and Im terrified of the potential bone damage from anastrazole, although the oncology guy was brilliant and said if I get any bone issues he wants me to ring his secretary and book in to see him. Im amazed cos it took 6 years to get my most recent dexa scan done and that was only because I requested it.I suspect  theyd forgotten to do it.Does anyone else feel like its too much to expect a person in this situation to try and keep on working??