Anastrozole has ruined my bones.

Hi There

I was diagnosed with stage 2 Oestrogen positive Breast cancer in 2016. After just 3 round of chemo, my ping pong ball sixzed tumour had disappeared and the cancer had left my lymph noed. After 8 rounds a mammogram had showed that though I was clear, calcium depositis on my breast might flare up into cancer and so I had a full mastectomy of the right breast and had 14 nodes removed. The nodes came back clear and the breast was cancer free though I did have dome precancerous tissue. I had had a complete pathological response which considerably increased my odd of not having a recurrence, After some months I had my healthy breast reduced from an f to a c cup to match my new implant and the removed tissue was completely cancer free. I then began anastrzole with zoladex injections to stop my periods. I also took part in the palbocciclib trial from 5 cycles until it caused my to reject 2 implants and developed sepsis.  

After a year on Anastrozole a dexa scan showed that I had gone from moderate osteopenia -1.7 to osteoporosis -2.6. I was horrified. I asked the oncologist what my chances of recurrence were. She said 5 to 10% if I take the anastrozole and 7 to 10% if I take nothing.  So I stopped taking it. I worry that I have gone against my oncologist but if I keep taking that drug I reduce my chanced of recurrence by 2% but will definitely ruin my bones. I haven't told my oncologist yet

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  • Hello, I took Anastrozole for 2.5 months  starting in May to reduce a breast tumour. It worked and I had a lumpectomy instead of the mastectomy the oncologist had told me at the beginning. I am now having radiotherapy. I had horrendous joint pain with Anastrozole. The pain still persists and I worry that I have permanent damage. It has been particularly problematic in my hands and my work is computer-based. I was told by the oncologist that I should take it for 10 years but I refused. I sympathise with you. It is a horrendous medication. 

  • I’m 5 years out from my right breast mastectomy, took Anastrozole for a total of 2 1/2 years.  My bones and muscles hurt, I was beyond exhausted and finally my hair, which came in super thick after chemo, began falling out on Anastrozole.  I never tell anyone to not mind their doctor.  I just decided to take the risk of quitting Anastrozole.  Cancer free, feel and look great.  72 years old and having a great life!!!!

  • Thank you so much for your reply. I am delighted you are clear after 5 years. Hopefully I will be too and without Anastrozole - I know I am taking a risk but it's my decision. I also take Alow Vera juice and I am taking Plutonium tablets which my homeopath friend gave me. She has been clear for 13 years and also rejected the Anastrozole. Once I finish the radiotherapy I am going back to doing yoga. You are so right, quality of life trumps all!!

  • Good for you Marietta54!!!!

    YES, Aloe, I drink Aloe with mango.  Yes on yoga, and great affirmations and thoughts

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