Hello Rubytuesday2

I'm sorry to hear that you're struggling with some of the common side effects of Letrozole. It's understandable that you would like to try and improve these as much as possible. 

Hopefully, some of our members who have experience with this medication will reply to share their hints and tips with you. In the meantime, whilst you're waiting for the information your breast care nurse has said she will send, you might like to give our nurses a chat and talk things through with them. I know they will be happy to listen and offer any advice, information and support they can. They're available Monday to Friday, 9am to 5pm on 0808 800 4040. 

I do hope that you can find something to help improve things soon. 

Best wishes, 
Jenn
Cancer Chat moderator 

Thank you I will call Monday

Hi. I think you've done really well to persevere so long on Letrozole. I managed 10 months, started June 2024, but had such awful side effects with pain and fatigue so I spoke to the oncologist who said as I'd persevered so long to change to Exemestane. I've been on them for 6 weeks and although there are still side effects, they're not as bad. I've also been on the national exercise referral scheme for 7 weeks which is helping a lot too. 

I took magnesium for a while when I was on Letrozole but then when I had a blood test the level was too high so I had to stop them again. The hormone therapy has affected my thyroid levels too which has also had a  knock on effect on the fatigue and joint pain so they've adjusted my meds for that too. I've been underactive for about 20 years but now it's going the other way. They're also going to keep an eye on my liver function because of the hormone therapy. 

Have a chat with your team to get their advice is best. They're always happy to advise and support. 

Hope you feel better soon. x

Hi. I think you've done really well to persevere so long on Letrozole. I managed 10 months, started June 2024, but had such awful side effects with pain and fatigue so I spoke to the oncologist who said as I'd persevered so long to change to Exemestane. I've been on them for 6 weeks and although there are still side effects, they're not as bad. I've also been on the national exercise referral scheme for 7 weeks which is helping a lot too. 

I took magnesium for a while when I was on Letrozole but then when I had a blood test the level was too high so I had to stop them again. The hormone therapy has affected my thyroid levels too which has also had a  knock on effect on the fatigue and joint pain so they've adjusted my meds for that too. I've been underactive for about 20 years but now it's going the other way. They're also going to keep an eye on my liver function because of the hormone therapy. 

Have a chat with your team to get their advice is best. They're always happy to advise and support. 

Hope you feel better soon. x

Thank you for your reply I will contact my nurse again