Long term use of Niraparib - ovarian cancer

I have been using Niraparib for 15 months and to date the main side effects are heart palpitations which I take bisoprolol for and fatigue. Has anyone else out there been on this drug for a while and if so how long and what if any side effects do you have? Also, if anyone has had to come off it why and for what reasons? Any feedback gratefully received, Katy 

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  • Hi Katy

    I was on Niraparib 200mgs for nearly 18 months but it stopped working for me, my ca125 didn't go above 20 whilst on it but it was steadily rising each monthly blood test, at the start of taking it I had a constant headache for two weeks, also fatigued and felt rubbish, but it did clear up and then I was fine with the dosage after being rushed into hospital in february this year for a blocked bowel, I  was taken off Niraparib and after a colonoscopy later, I now have had a stoma for 6 months due to ovarian cancer recurrence in my large bowel, I've just completed my 2nd lot of chemotherapy ( carboplatin & caelyx) 6 months of 4 weekly, I'm now awaiting a scan on 28th October to see if I'm all clear for now, if so it will be 3 monthly scans. I'm not sure what will happen if I'm not, but will cross that bridge if im not!  I hope all goes well for you, stay strong, ask your oncology questions about your treatments no matter how silly you think the questions are, as they are best placed to give you answers as everyone's journey isn't the same, wishing you all the best.

    Rose xx

  • Hi Rose, Thanks for your comments above. I have also suffered with a lot of bowel obstructions due to wide spread adhesions and have to manage what and when I eat really carefully. Fingers crossed for your scan on 28/10. I completely agree with your approach of ask questions and we are all different in terms of our cancer journeys. Wishing you all the best, Katy 

Reply
  • Hi Rose, Thanks for your comments above. I have also suffered with a lot of bowel obstructions due to wide spread adhesions and have to manage what and when I eat really carefully. Fingers crossed for your scan on 28/10. I completely agree with your approach of ask questions and we are all different in terms of our cancer journeys. Wishing you all the best, Katy 

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