Rising CA125 after 1st chemo but clear CT???

I had optimal debulking surgery for stage 3A low grade ovarian cancer in June. Pre surgery levels of CA125 were 478. Post surgery 311. This week, 19 days after chemo 1 (paclitaxel and carboplatin) it was leapt to 513!! I'm obviously horribly concerned by this as I'd expected a drop! 
 

I had a CT scan on 18 August ( a week or so before blood tests) which showed no signs of any disease. 

 

Can anyone give their experience of this? I'm so worried and scared now. I have had some constipation since chemo one but no infection or obvious cause for rise. 

  • Hi Kay1985,

    Do make sure you discuss this with your doctor/specialist when you can - talk through your concerns and see what they say; they will of course be best placed to advise specifically to your situation.

    Meanwhile hopefully you will also receive further replies here, particularly if there are others with similar experience to share.

    Wishing you all the best,

    Ben
    Cancer Chat Moderator