Hi all, I'm new to this group, I've been on letrizole for breast cancer,  a year now. I am thinking of stopping taking it as it has, not only, given me severe swelling in my hands and feet but I am also experiencing eye problems. I have just had one eye operation for cataract , I need the second eye doing now but I am now also having problems wit tears in the virtuous fluid, causing black marks in my vision. Insomnia and night sweats are ruining my relationship with my partner too. Im struggling to work. My doctor told me to exercise more - I look after two horses and walk dogs daily. Also after walking my hand swell and throb. Does anyone else have these problems. My consultant says I must stay on letrizole and is reluctant to give me any figures on my chances if I stop taking it.