I was recommended to have a left breast mastectomy in November2017 as it was thought I had DCIS throughout the breast. Thank goodness I went ahead as 1.7mm of invasive cancer was found.  Initially I was put on Tamoxifen, but was switched to Letrozole in April 2019, apparently due to blood test indicating I was post menopausal.  I am 54, 55 in January.  Hot flushes were a nightmare with Tamoxifen so I was hoping for the best with Letrozole. Sadly, the hot flushes are almost as prevalent but the bone, joint and muscle pain are really get me down. I feel like a 75 year old! :(  My bone scan in April showed I already have osteopenia, so continuing with Letrozole scares me. I am seriously considering coming off them. Are there any less scary alternatives?