This is me ! Suffering from Letrozole side effects

Hi. I'm 68 and am a pensioner with several health issues and am a carer for my husband of 49 years & who is 83. Although I found a breast lump in August 2023 it wasn't located or confirmed until late January this year. Surgery followed but I count myself very fortunat. Surgery went well, as did radiotherapy & chemo wasn't required.

It is only now that I am taking a breath before gearing up for Christmas, that I can look back on this year and think about myself and what this diagnosis has meant for me. It might sound surprising but at no point was I scared of the diagnosis or the possible outcomes. I am the type of person that likes my information straightforward and I have learned over time to not jump hurdles before you get to them. That has helped me enormously. Focussing on my family has stopped me worrying about day to day issues with my treatments.

Finally I must pay tribute to both my wonderful husband and one of my best friends. Worried as he was,  hubby never was anything less than supportive even though he wasn't physically able to accompany me to any of my appointments or treatments. My friend was the first person I told as she has had two bouts of breast cancer over a period of 25 years. She was brilliant with her care & support. I am so lucky. 

So why am I feeling sorry for myself now?  It maybe because I have recently started to get sciatica and other joint & muscle pain. The sciatica is unrelenting from my butt to my left big toe. The past few days have been so miserable particularly at night.  Any of you out there suffering from what appears to be the side effects of the Letrazole I'm taking?  If so do you have any tips or advice to relieve the pain?

  • Hi

    It is certainly the Letrozole working its magic! My fibromyalgia pain has intensified since starting this medication and some days I can hardly walk with the fatigue (after 20 radiotherapy sessions) and joint and muscle pain. I take the occasional dose of paracetamol which dulls it for about two hours but pain killers are not a permanent solution. I try to move about and take a short walk with the help of my walking stick. Distraction and having periods of rest in the afternoon are my only solution. I am 81 and I look after my 82 year old husband who is in poor health but I am managing to do so without external help. 

    My lumpectomy and axillary clearance went well as did the radiotherapy until two weeks ago when I started to experience extra numbness in my fingers and toes plus sharp stabbing pains in the operation areas. As a result I have given up driving and sold our car. This is a small sacrifice for keeping those rogue cells at bay but nevertheless it was a wrench because my husband always enjoyed seeing the outside world and a trip in the countryside was his only pleasure. Fortunately we have a good local taxi firm so life goes on!

    I would mention your symptoms to your designated breast cancer nurse. I have a follow up telephone appointment next month so I shall ask her for her suggestions but I anticipate that they will be "keep active and take painkillers". As regards sciatica my GP always hands out a patient exercise sheet and  tries to arrange sessions with the hospital physiotherapy department (usually a six month wait!)

    Best wishes and sorry I can't be of much help. 

  • Hi, anastrozole for me and my feet, knees and ankles are the worst. Mornings I have to walk down the stairs sideways with two feet on each stair. Got to love aromatase inhibitors ! I was told to take Glucosamine chondroitin with msm to help with joint pain. Sometimes the cure is worse than the disease x

  • Hi I agree...  How awful for you ...I was hoping Anastrozole might be better ..Ummm ..i guess there all pretty awful .
      Keep going ..now matter what !
    Regards Nina