Thank you for your reply. My husband has seen multiple GPs at our practice, however, most are locums as his " named GP " is now semi retired, and only works two days a week.  We tried to make yet another appointment  last Friday to see him, however, we were told that the only appointment available is  in five weeks!  It is an absolute nightmare. I am a qualified nurse,  now retired, and feel at a loss at what to do,  so this is why I thought that maybe, there would be someone who had been in this position in the past, and could help. I thought about A&E as a last resort. I know he needs bloods taking and full body  MRI, and, or CT scans in order to identify what is going on, and hopefully diagnose. To see your husband in obvious pain and distress, and,  getting worse each day is horrific. Thank you again for reading and replying to my post.