38yo stage 4 oesophageal cancer (terminal)

My partner of 18 years gave birth to our 3rd child,  on 15th May 2022, during pregnancy she was having lots of problems swallowing and experiencing chronic pain behind her ribcage cage.

The medics kept saying it was hormonal and would return to normal after birth.

 

Unfortunately this was not the case and 5 weeks later had the tragic news it was cancer of the oesophagus stage 4 mets to liver, right lung and multiple lymph nodes.

I have posted on site previously as her response to her treatment was making me very confused. She has had 5 of her six cycles now and still has no negative effects to the treatment. No Nausea, no tiredness etc.

Other than knowing she has cancer, you wouldn't know if that makes sense.

She is on the max dose of cistaplatin, herceptin and x3 tablets twice a day ( the name I've forgotten 

I write this today following a very positive scan result. The scan was done mid way through her 3rd cycle but due to staffing issues got results today.

All of the tumours are shrinking considerably, the primary tumour unable to give specific sizes but report says notable.

 

The liver has shrunk from 3cm to 1.8 cm

 

The lungs only minimal shrinkage but no growth.

All of the lymph nodes have shrunk some by considerable amounts 19mm down to 7mm

 

Is this kind of response rare ????

Her prognosis was initially 6/12 months, she is 5 months in now and goes from strength to strength.

 

Has anybody else experienced similar.

I'm obviously very pleased by the news but incredibly confused as her treatment was described by her consultant as Palliative 

  • Hello stmike

    I'm so glad to hear that you've had some positive news from your wife's most recent scans. It's understandable that you may be experiencing a whole range of emotions right now. 

    I don't know if you've read [@davek]‍ story here on the forum. Click on his profile and you'll see that Dave was diagnosed with stage 4 oesophageal cancer in 2013 and was told it was incurable. Dave's most recent scans in July this year show that he is still "most probably cancer free". Sometimes patients will have an extraordinary response to treatment and I truly hope that things continue to progress well for your wife. 

    If you want to talk things through with one of our nurses at any point you're welcome to call them on 0808 800 4040, Monday to Friday 9 am to 5 pm. 

    Sending best wishes to you both, 
    Jenn
    Cancer Chat moderator 

  • That is without doubt the best news I've read in a long time ,Lets hope she goes from strength to strength ,sending you all my very best thoughts and wishes x

  • Thank you Jenny.

    I know it's amazing it really is but my brain just can't process any of it.

    Before we knew it was cancer she was in agony climbing the walls, couldn't even drink a fortisip.

    Then after 2 cycles she could eat anything and I mean anything. No stent etc.

    She's put all her weight bk on, and using the gym 4 times a week.

    We have 3 children and the older 2 have totally forgotten there mam is ill.

    She has an infusion every 3 weeks for almost 10 hours, soon as she's unhooked boom back to business.

    Then the results are amazing. I know this sounds sick but I was expecting to be nursing her in bed at this stage not dropping her off at nightclubs and gyms.

    Her last cycle she had infusion on the Friday, then very next day was boozing it up all day at gay pride

    I have no idea how she does it.

    These amazing results were only after 2 and half cycles, well technically not even that as her first cycle was a disaster our heads were all over and she should have had 3 tablets twice a day, she was having 1.

    Just couldn't process information after the shock.

  • That is truly amazing, sounds like remarkable things are happening treatment is definitely getting better in the last few years ,a friend of mine is doing really well on just Immune boosting therapy and a few other things thrown in ,she didn't want chemo so she is trying different things and as I say its working very well .

  • Hi,

    That's fantastic news! 
    I asked a similar question of one of the research scientists during a visit to the CRUK labs in Manchester a couple of years ago. He said that I was probably a super responder to the EOX chemo regime. I knew from my own work that I was a statistical outlier who would be excluded from the published average survival rates but that was the first time I'd heard the term.

    There's an interesting article on the topic with links to research papers here www.cancertodaymag.org/.../

    My oncologist, who lectures on upper GI cancers, sometimes introduces me to his medical students and junior doctors as an example of why you shouldn't apply survival statistics to individual patients. 

    I hope your wife continues to surprise the professionals.

     

    Best wishes

    Dave