A family member in their late 70's has been diagnosed with prostate cancer spread to bones.
Initial psa of 700, a course of hormone therapy tablets was prescribed followed by the first hormone therapy injection. The next injection was due 6months later. Blood tests 2 months after initial injection showed their psa dropped to 39. 
all seemed good ..

fast foward another month so 3 months after initial injection and we have discovered their psa level is back up to 700 which is obviously indicative of hormone therapy resistance. (Discovered due to recurrence of symptoms similar to initial diagnosis) .. We are currently waiting for an app with urology and oncology to figure out the next treatment option but this is extremely worrying. We thought we had at least 2 years before this happened... just wondering has anyone else come across hormone therapy resistance so early??? And if so what was the outcome? Did another type of hormone therpay injection work instead?

we are feeling very disheartened..