Hi Alyson, welcome to the forum, but I'm so sorry for why you are here. This disease does not pick favorites for sure and how tragic that your sister is so ill at such a young age. Added to that are her three young children who will be left without their mother to be there for them as they grow up and make their way in the world. I wish there was something I could say to ease your pain, but there really isn't.anything right about this. About the only thing I can say is that there are many others here on the forum who are facing some of the worst challenges in their lives that none of them ever expected to have to face. You are not alone here and people are very caring and supportive on this forum. Come on here any time and write about your pain and frustrations, rant, cry, and do whatever you need to do to get through this. I can tell by your post that you have family there and all of you need to support one another as you take this journey that no one ever wants to be on.

Sending you hugs to share with your sister and her children, as well as the rest of your family.

Lorraine 

It's 3.30am in the morning - a time I'm often awake. My partner has stage 4 cancer and I know what you're going through. Our lives changed in July 2013 with the diagnosis and it's been up and down ever since. All I know how to do is hold on to the good moments,be there every step of the way and take each moment has it comes. Looking ahead is too scary. It's lonely and support around so helps. We have 4 sisters between us and we need them as I'm sure your sister needs you.